Every peptide in the wiki. A to Z.
There are hundreds of different types of peptides. Most are noise. This is the list of peptides people actually run. A peptide guide ranking the best peptides by evidence, not by who sells them. 20 profiles with protocols, peptide side effects, and dosing. Whether you are researching peptides for beginners or comparing compounds you already know, every profile here tells you what the data actually says.
Types of peptides by goal
There are hundreds of different types of peptides. Most are research dead-ends or relics from abandoned trials. The ones below are the types that keep coming up in every group chat, subreddit, and late-night search. Sorted by why people take them.
This is the Ozempic conversation. Semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) are FDA-approved GLP-1 receptor agonists with the largest clinical trial datasets on this entire list. Semaglutide posted ~15% weight loss in the STEP trials. Tirzepatide outperformed it head-to-head with ~22.5% at the highest dose. Retatrutide is the triple agonist (GLP-1/GIP/glucagon) that posted 24.2% in Phase 2. Phase 3 is ongoing. Evidence tier: Strong (sema, tirz) / Emerging (reta).
See weight loss peptides Recovery & healingBPC-157 and TB-500 are where most people start. BPC is a gastric peptide fragment with hundreds of animal studies showing gut and tendon repair. TB-500 is a thymosin beta-4 fragment that travels systemically. People stack both because they work different pathways. Neither has completed a human clinical trial, but the community data is dense enough that they dominate every beginner conversation. Evidence tier: Early.
See recovery peptidesGHK-Cu (copper tripeptide-1) is the standout. Your body produces it naturally to signal collagen and elastin production, but levels drop sharply after your mid-twenties. Both injectable and topical forms exist. The skin data is the strongest in this category, with multiple small human trials showing wound healing acceleration and collagen density improvement. Melanotan II produces a real melanin-based tan without UV exposure, but darkens moles, raises libido, and causes nausea at loading doses. Evidence tier: Emerging.
See beauty peptides LongevityThe most speculative shelf. Epithalon supposedly activates telomerase, the enzyme that lengthens telomere caps on your DNA. The data comes almost entirely from Russian research groups with limited Western replication. MOTS-c is a mitochondrial-derived peptide that improves insulin sensitivity and exercise capacity in animal models. SS-31 (elamipretide) is actually FDA-approved for Barth syndrome, making it the only approved mitochondrial drug. Longevity use is off-label. NAD+ is not technically a peptide, but it shows up in every protocol conversation. Evidence tier: Mixed (SS-31 is Strong, the rest are Early).
See longevity peptidesSemax and Selank are both approved in Russia and used off-label everywhere else. Semax boosts BDNF, dopamine, and serotonin. Originally developed for stroke recovery, nootropic use is off-label. Selank modulates GABA without sedation or dependence. No crash, no hangover. They are often run together. Evidence tier: Emerging (Russian clinical data, limited Western replication).
See cognitive peptides Sexual healthPT-141 (bremelanotide, brand name Vyleesi) is the only FDA-approved peptide specifically for hypoactive sexual desire disorder (HSDD) in premenopausal women. It works on the melanocortin system in the brain, targeting desire itself rather than blood flow. The approved route is subcutaneous injection. Evidence tier: Strong.
See sexual health peptidesFrequently asked questions about peptides
Because these are the ones people actually run. The list covers every compound with meaningful human evidence, an FDA interaction, or enough real-world use that you will encounter it. We add a peptide when evidence justifies it, not on request.
Tier 3 means approved by a major regulator (FDA, EMA) for a human indication. Tier 2 means human clinical trial data exists, phase 2 or phase 3, even if not approved. Tier 1 means early research only: rodent data, case reports, or abandoned trials. Tier does not mean safe or effective for your use case. It means how far along the evidence is. The methodology page explains how we grade.
Five compounds on this list have FDA approval for at least one indication: semaglutide (Ozempic/Wegovy for T2D and obesity), tirzepatide (Mounjaro/Zepbound for T2D and obesity), PT-141 (Vyleesi for HSDD in premenopausal women), tesamorelin (Egrifta for HIV lipodystrophy), and SS-31 (elamipretide for Barth syndrome). Approved does not mean approved for the reason you want to use it.
It depends on where you live and what you are buying. FDA-approved peptides are legal with a prescription. Research peptides sold “for research purposes only” exist in a grey area in many jurisdictions. Some countries (Australia, for example) have moved to restrict or schedule specific peptides. This wiki does not sell peptides and cannot give legal advice. Check your local regulations.
FDA-approved peptides (semaglutide, tirzepatide, PT-141, tesamorelin) require a prescription. Compounded versions may be available through telehealth clinics. Research-grade peptides are sold without a prescription in many countries, but this does not mean they are regulated or guaranteed for purity.
BPC-157 is where most people start because the side-effect profile in community reports is mild (occasional headache, nausea at higher doses) and it does not affect hormones. That said, it has zero completed human trials. For a peptide with actual human safety data, semaglutide and tirzepatide have the largest trial populations. “Safe” is relative to your specific situation. Talk to a clinician.
Steroids are synthetic hormones that directly replace or supplement your body’s testosterone, estrogen, or cortisol. Peptides are signaling molecules that tell your body to do something it already does: release growth hormone, repair tissue, or suppress appetite. Peptides do not cause the androgenic side effects (acne, hair loss, virilization) associated with anabolic steroids. They are different classes of compounds with different mechanisms, side-effect profiles, and legal statuses.
Approved means a regulator signed off on it for one specific condition, under one brand name, at one dose. Tesamorelin is approved for HIV lipodystrophy, not general belly fat. Whether a clinic will prescribe it off-label is a separate question that varies by jurisdiction and provider.
Search the wiki for the name or an alias. If it is not indexed, we have not found enough evidence to write about it honestly. The chart puts everything we do cover side by side on dose, cadence, and storage.
About this peptide list
This page is maintained by the vialprep editorial team. Content is reviewed against PubMed, ClinicalTrials.gov, and FDA databases. Evidence tiers are assigned using the vialprep methodology. Last reviewed September 2026. Clinical citations are linked inline where available. This page is not medical advice. Talk to a licensed clinician before starting any protocol.